diff options
Diffstat (limited to 'gnu/packages')
-rw-r--r-- | gnu/packages/bioinformatics.scm | 121 |
1 files changed, 121 insertions, 0 deletions
diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm index fa22399136..4bed2e4fe8 100644 --- a/gnu/packages/bioinformatics.scm +++ b/gnu/packages/bioinformatics.scm @@ -130,6 +130,7 @@ #:use-module (gnu packages pdf) #:use-module (gnu packages perl) #:use-module (gnu packages perl-check) + #:use-module (gnu packages perl-web) #:use-module (gnu packages pkg-config) #:use-module (gnu packages popt) #:use-module (gnu packages protobuf) @@ -4999,6 +5000,126 @@ be of arbitrary length. Repeats with pattern size in the range from 1 to 2000 bases are detected.") (license license:agpl3+))) +(define-public trinityrnaseq + (package + (name "trinityrnaseq") + (version "2.13.2") + (source (origin + (method git-fetch) + (uri (git-reference + (url "https://github.com/trinityrnaseq/trinityrnaseq.git") + (commit (string-append "Trinity-v" version)) + (recursive? #true))) + (file-name (git-file-name name version)) + (sha256 + (base32 + "1qszrxqbx4q5pavpgm4rkrh1z1v1mf7qx83vv3fnlqdmncnsf1gv")))) + (build-system gnu-build-system) + (arguments + (list + #:test-target "test" + #:modules + '((guix build gnu-build-system) + (guix build utils) + (ice-9 match) + (srfi srfi-1)) + #:make-flags + #~(list (string-append "CC=" #$(cc-for-target))) + #:phases + #~(modify-phases %standard-phases + (replace 'configure + (lambda _ + (setenv "SHELL" (which "sh")) + (setenv "CONFIG_SHELL" (which "sh")) + ;; Do not require version.h, which triggers a local build of a + ;; vendored htslib. + (substitute* "trinity-plugins/bamsifter/Makefile" + (("sift_bam_max_cov.cpp htslib/version.h") + "sift_bam_max_cov.cpp")))) + (add-after 'build 'build-plugins + (lambda _ + ;; Run this in the subdirectory to avoid running the + ;; tests right here. + (with-directory-excursion "trinity-plugins" + (invoke "make" "plugins")))) + ;; The install script uses rsync, provides no overrides for the + ;; default location at /usr/local/bin, and patching it would change + ;; all lines that do something. + (replace 'install + (lambda* (#:key inputs #:allow-other-keys) + (let ((share (string-append #$output "/share/trinity/")) + (bin (string-append #$output "/bin/"))) + (mkdir-p bin) + (copy-recursively "." share) + (delete-file (string-append share "/Chrysalis/build/CMakeFiles/CMakeOutput.log")) + (delete-file (string-append share "/Inchworm/build/CMakeFiles/CMakeOutput.log")) + + (wrap-program (string-append share "Trinity") + `("R_LIBS_SITE" ":" = (,(getenv "R_LIBS_SITE"))) + `("PERL5LIB" ":" = (,(getenv "PERL5LIB"))) + `("PYTHONPATH" ":" = (,(getenv "GUIX_PYTHONPATH"))) + `("PATH" ":" = + ,(cons (string-append share "/trinity-plugins/BIN") + (filter-map (match-lambda + ((name . dir) + (string-append dir "/bin"))) + inputs)))) + (symlink (string-append share "Trinity") + (string-append bin "Trinity")))))))) + (inputs + (list blast+ + bowtie + fastqc + hisat + htslib + icedtea-8 + jellyfish + kallisto + multiqc + perl + perl-uri-escape + python-numpy + python-wrapper + r-ape + r-argparse + r-biobase + r-ctc + r-deseq2 + r-edger + r-fastcluster + r-glimma + r-goplot + r-goseq + r-gplots + r-minimal + r-qvalue + r-rots + r-sm + r-tidyverse + rsem + salmon + samtools + sra-tools + star + zlib)) + (propagated-inputs + (list coreutils + gzip + which)) + (native-inputs (list cmake)) + (home-page "https://github.com/trinityrnaseq/trinityrnaseq/wiki") + (synopsis "Trinity RNA-Seq de novo transcriptome assembly") + (description "Trinity assembles transcript sequences from Illumina RNA-Seq +data. Trinity represents a novel method for the efficient and robust de novo +reconstruction of transcriptomes from RNA-seq data. Trinity combines three +independent software modules: Inchworm, Chrysalis, and Butterfly, applied +sequentially to process large volumes of RNA-seq reads. Trinity partitions +the sequence data into many individual de Bruijn graphs, each representing the +transcriptional complexity at a given gene or locus, and then processes each +graph independently to extract full-length splicing isoforms and to tease +apart transcripts derived from paralogous genes.") + (license license:bsd-3))) + (define-public repeat-masker (package (name "repeat-masker") |